Cyclodextrin and Their Derivatives as Stationary Phases for Separation of Enantiomers by Capillary Gas Chromatography

Authors

  • I. Spanik Department of Analytical Chemistry, Faculty of Chemical Technology, Slovak Technical University, Bratislava, Slovak Republic
  • J. Krupcik Department of Analytical Chemistry, Faculty of Chemical Technology, Slovak Technical University, Bratislava, Slovak Republic

Abstract

The review deals with the use of cyclodextrins (CD) and their derivatives as stationary phases in gas chromatography for separation of enantiomers of organic substances. Unlike the native cyclodextrins, their alkyl, acyl and tert-butyl(trimethyl)silyl derivatives are successfully used as stationary phases in capillary gas chromatography. The enantioselectivity of the CD derivatives can be changed both by the nature of silyl substituents and by the type of CDs. alpha-, beta- and gamma-CD derivatives with bulkier substituents in positions 2 and 3 than in position 6 exhibit a specific enantioselectivity compared with those containing equal substituents.

Published

2000-02-15

How to Cite

Spanik, I., & Krupcik, J. (2000). Cyclodextrin and Their Derivatives as Stationary Phases for Separation of Enantiomers by Capillary Gas Chromatography. Chemické Listy, 94(1). Retrieved from http://www-.chemicke-listy.cz/ojs3/index.php/chemicke-listy/article/view/2544

Issue

Section

Articles